Bohle granulation systems ensure easy and efficient operation. Only minor residues remain in the process container after discharge, which guarantees maximum yield. These properties apply to the entire granulator range from laboratory granulator to production scale single pot granulators with batches of up to 750 kg. L.B. Bohle offers many options and product expansions for wet and dry granulation to configure the system customized for special application.
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Continuous processes are strongly increasing in the pharmaceutical industry. In 2011, L.B. Bohle introduced the first Bohle Conit Granulator BCG® - a twin screw granulator with a downstream dryer. A new version of the twin screw granulator BCG was unveiled in 2017!
Using a tangential fluid bed system represents state of the art technology in pharmaceutical manufacturing for particle coating, granulation and drying.
With the innovative and patented Bohle Uni Cone BUC® process a complete fluidization is assured which leads to a high coating uniformities and high yields in the final product due to the absence if particle twinning. Bohle Uni Cone BUC ® is the productive, practical and precise alternative to conventional Wurster processing.
The BFS features a broad range of extension options for Bottom Tangential Spray Granulation as well as Bottom Tangential Spray Coating. All production systems are 12 bar shock pressure resistant.
Insiders quickly recognise machines from L. B. Bohle: easy handling, continuous production and small footprint are the typical features of the products. With the Bohle Rpller Compactor BRC 100, a drying granulator is set to celebrate its world premiere at ACHEMA 2012. The BRC 25 was introduced in 2014.
The individual components of the High Shear Granulator GMA, wet sieve BTS, Fluid Bed System BFS and Bohle Uni Cone BUC®, cyclone separator and dry sieve BTS are optimally integrated into the Compact Unit. This integration covers process, cleaning, control and explosion protection as well as qualification.
The Compact Unit is a compelling solution when traditional wet granulation must be realized economically and ergonomically. Featuring many technological advances and inherent safety considerations, the Compact Unit creates an industry benchmark.
Small footprint, flexible application and smooth production processes are decisive criteria for investment in the pharmaceutical granulation system. In this respect, L.B. Bohle sets standards with the Compact Unit.
The Granumator® GMA is a granulation system specifically optimized for pharmaceutical applications. The impeller is designed for high shear and compression, ensuring effective granulation. The chopper prevents excessive granule growth and distributes the granulating liquid within the product.
The High Shear Granulator GMA is designed for through-the-wall installation. The container is connected to the system head via electrically driven lifting cylinders and can be lowered for inspection, for example. The granulation system GMA is 12 bar shock pressure resistant.
The VMA single pot granulator is a granulating and drying system specifically optimized for pharmaceutical applications. The Vagumator® single pot systmes are designed for closed, dust-free processing of pharmaceutical granules from charging through dicharge including in-line milling.
Mixing, granulation and drying cycles are completed in a single machine under contained conditions.
The impeller, with its high shear and compression, ensures effective granulation. The chopper prevents excessive granule growth and distributes the granulating liquid within the product.