High-shear single-pot granulation has been used in the pharmaceutical industry for many decades. Single-pot granulation combines the mixing, high-shear wet granulation and drying (vacuum drying, carrier-gas drying, or microwave drying) all in one process bowl. L.B. Bohle's single-pot granulation portfolio includes R&D systems for small production volumes as well as production-scale systems.


Granulation with the Bohle Single Pot Granulator

The VMA product range includes classic single-pot granulators with agitator and chopper units and a top drive. Two stirrers produce the shearing action and loosen the product. This helps to prevent clumping and ensures that the resulting granule is of optimum quality. The GMP-compliant process bowl with a double shell is the core of the VMA.

The main aggregates are integrated in the lid of the granulation pot (top drive). The process bowl is emptied through a cone-shaped sieve (BTS 200) via the floor outlet into a container (IBC). Recipe-controlled cleaning is carried out automatically. The VMA produces batch sizes from 20 to 960 litres and can be installed in explosive atmospheres.


Benefits of the Single-Pot Granulator at a glance:

  • Safe production inside a closed bowl in a vacuum
  • High mixing and granulation efficiency (even for low doses of active agents at < 1%)
  • Drying at low temperatures
  • Small product contact surface for fast, easy cleaning and fast product switching
  • Efficient solvent recovery through cooling water

Bohle Single Pot Granulator Product Gallery

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Technical Data: Single Pot Granulator

  VMA 70 VMA 300 VMA 600 VMA 1200
Overall dimensions (LxWxH) 1800x1300x2500 2290x1650x2950 2525x1850x3350 3365x2150x4400
Control system PLC, Visualisierung In Touch von Wonderware

The Bohle  product range of Single Pot Granulators contains:

  • VMA 10
  • VMA 70
  • VMA 300
  • VMA 600
  • VMA 1200

Your contact at L.B. Bohle for the Single Pot Granulator

 

Ingo Küsel

Area Sales Manager

This email address is being protected from spambots. You need JavaScript enabled to view it.
+49 2524 - 93 23 0
 


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