In the pharmaceutical industry, one term is becoming increasingly important: containment. It describes the process of containing a substance within a defined space, a method that is suitable for protecting operators and the environment in case of high toxicity and product reactivity. At the same time, containment prevents dust, gases or vapours from being released into the environment and contaminating the product.

More than 60 percent of pharmaceutical products are produced as tablets, capsules, lozenges or similar solids. Especially in new products the active pharmaceutical ingredients (APIs) are becoming increasingly more potent. In some markets, the segment for high potency active pharmaceutical ingredients (HPAIs) is growing in the double-digit range, especially driven by oncology medication.

L.B. Bohle offer comprehensive containment applications

For many years, L.B. Bohle has been known as a supplier of all-in-one solutions. L.B. Bohle offer premium technology not only for standard machinery, but above for complex containment applications with a high degree of individuality, Bohle proves its exceptional design position. Thus, the containment applications create an everyday added value for the customer.

Fully-integrated containment applications

L.B. Bohle offer containment solutions for both handling and process mines.  In the handling sector, for example, a lifting column and containment valves can be used for feeding the product as well as an integrated containment valve for the transfer of the granules into a receiving container.

Containment coater according to customer specifications

In the field of process machines, L.B. Bohle developed a containment coater of the BFC series exactly according to customer specifications.

The containment version of the BFC 100 enables operation in closed driving mode thanks to:

  • automatic nozzle adjustment (stroke and angle)
  • infra-red product temperature measurement
  • charging via a container flap
  • the connection for cleaning the container flap and the charging pipe (also available for discharge)
  • the connection for drying the container flap and the charging tube
  • the sampling lance
  • side doors with inflatable gasket (also standard for BFC)
  • the demountable nozzle holder. This results in great advantages when it comes to cleaning.

Roller compactor in a containment execution

The BRC 100 Containment is proven through the typical BRC attributes. Just like the standard version, the Containment BRC features a state-of-the-art electro-mechanical drive, completely eliminating the need for hydraulics.
In addition, the special version is equipped with the latest and fastest control which enables fully-automated operation. The BRC is very user-friendly and low-maintenance, with very short set-up times.

The highlights of the BRC containment at a glance:

  • equipped for the containment level OEB 5
  • integrated insulator unit in the compacting unit with corresponding vacuum monitoring
  • glovebox with security prompt for the removal of scabs
  • containment port for the collection of scab samples
  • containment port underneath the sieve unit for the removal of granules
  • convenient access, since no complete insulator unit is installed around the entire compactor
  • residue-free removal of product by integrated WIP equipment (WIP is also integrated in the standard version).
previous arrow
next arrow
Full screenExit full screen
ArrowArrow
Slider

Protect your employees, products and the environment reliably - put your trust in containment applications from L.B. Bohle.

Continuous ManufacturingTechnology Center

Continuous Manufacturing

From Powder to the coated tablet: The unique feature of the production unit QbCon® is that the tablet production can be implemented either without granulation or with dry or wet granulation, in one system.

Test QbCon® Now

Complete Solid Dosage ProductionService Center

The Bohle Service Center enables the presentation and testing from our machines as well as the executions of workshops and tutorials.

to Service Center

 

InnovativIssue: 1-2019

The current issue of the Bohle Innovativ has been published.

Read the latest issue

Download Innovativ

view all

Events & Exhibitions2019

L.B. Bohle exhibits at several events worldwide.

View all trade fairs