L.B. Bohle Maschinen + Verfahren from Ennigerloh, Germany, has developed solutions for the continuous production in the pharmaceutical industry. Bohle started off with a continuous granulator and has now come up with a twin-screw extruder with a vacuum contact dryer. The extruder has been tested by scientists at Bonn University. An interview with Prof. Dr. Klaus-Jürgen Steffens on the extruder and tests follows below.
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Compact Granulation unit keeps things running smoothly
Granulation has often been plagued by blocked transfer lines, the difficulty of having to operate the system at multiple levels and the time-consuming cleaning. A new granulation unit sets new standards in wet granulation.
Almac Clinical Services has launched a new web-based, Shipping Temperature Electronic Monitoring System (stems) for pharmaceutical and biotech industries. This service is for the management of temperature controlled shiments for clinical trials and is designed to save time and reduces costs.
The BTC tablet coater, according to L.B. Bohle, features: Up to 35 percent shorter processing times than conventional coating systems. An elogated coating pan to provide a larger tablet spraying surface for delivery of more solution and reduction of process times...
The scourge of the flagging global economy has not prevented consumers from stocking their medicine cabinets with vitamins and supplements. According to a report by market research firm, BCC Research, this segment of the nutraceutical market is forecast to reach more than $48 billion by 2013.
About 70 percent of pharmaceutical products are solid-dosage forms — tablets, capsules, oral powders, and powders for solutions or suspensions.
No pharmaceutical processing line is complete without a mill for handling both active and inactive materials for the manufacture of tablets and other products. To date, cone mills and hammer mills still play some of the largest roles in pharmaceutical processing due to their versatility.
Both cone mills and hammer mills have smaller footprints in processing environments where space is at a premium. Many of these mills are now equipped with integrated lifting columns, allowing them to adjust to fit into virtually any processing line. Further, their portability allows manufacturers to increase efficiency by moving — and sometimes dismantling — them quickly for cleaning.
Here are some of the latest trends in cone and hammer milling, including a look into how one manufacturer increased its processing efficiencies by installing three new hammer mills.
Compliance with GMPs (good manufacturing practices) is paramount for nutraceutical manufacturers seeking to produce high-quality dietary supplements.