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Terms

Sieving

Process for chopping agglomerates into powder or for classification of different particle sizes.


Single pot granulator

The granulation system specifically optimized for pharmaceutical applications is an impeller with high shear and compression and ensures effective blending. The granulator offers optimal conditions for wet granulation of high - quality pharmaceuti cal products.


Substance

Pharmacological substance with a healing, relieving or preventive effect for the human body.


Sugar - Coating

Applying a sugar solution to tablets. Sugar - Coating is performed using a coater or a coating tank.


Tablet

Pharmaceutical containing one or several substances. For the coating of coated tablets, a coater or fluid bed system and Bohle Uni Cone BUC® can be used.


Tangential - spray coating

With tangential - spray coating, the nozzles are arranged at the product container wall, directly above the air distributer plate. An advantage of this technology is the rapid maintenance and change of nozzles. In contrast to top - spray technology, denser granules can be produced.


Technology Center

L.B. Bohle inaugurated the Technology Center at the headquarter in Ennigerloh. Together with an consortium from industry and academia a continuous production unit was developed under the guidance of L.B. Bohle. The production line is designed as a flexible layout concept, allowing exchanging or removing single unit operations. In this way the three most commonly production layouts direct compression, wet granulation and dry granulation can be realized.

L.B. Bohle developed following machines for the Technology Center:

  • Bohle Continuous Granulator BCG
  • Bohle Continuous Dryer BCD
  • Bohle semi-kontinuierlicher Coater KOCO®

Through - the - wall installation

The aim of the through - the - wall installation is to obtain a strict separation of production and technology. This allows for production equipment according to GMP standard


Validation

Demonstration and documentation according to the GMP principles


VDMA

German Engineering Association. As medium - sized pharmaceutical machine builder, L. B. Bohle Maschinen + Verfahren GmbH is a member of the VDMA .


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Continuous ManufacturingStart Your Continuous Manufacturing with QbCon

Continuous Manufacturing

From Powder to the coated tablet: The unique feature of the production unit QbCon® is that the tablet production can be implemented either without granulation or with dry or wet granulation, in one system.

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Complete Solid Dosage ProductionTest Our Machines in the Service Center

Solid dosage production

The Bohle Service Center enables the presentation and testing from our machines as well as the executions of workshops and tutorials.

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